Sicca syndrone

by Nathan Wei, MD, FACP, FACR

Nathan Wei is a nationally known board-certified rheumatologist and author of the Second Opinion Arthritis Treatment Kit. It's available exclusively at this website... not available in stores.

Click here: Second Opinion Arthritis Treatment Kit

Sicca syndrome is not synonymous with Sjogren’s disease.

Sjogren’s disease refers to an autoimmune disorder which is a close cousin to systemic lupus erythematosus. Patients with Sjogren’s disease have abnormal antibodies and inflammatory damage involving multiple organ systems.

Sicca syndrome on the other hand consists of the following two features:

o Keratoconjunctivitis - Dry eyes with reduced tear production with gritty or sandy sensation under the lids; red eyes; photosensitivity

o Xerostomia - Decreased saliva production leading to difficulties with chewing, swallowing, and even speech; abnormality in taste and smell; dental caries; mucosal burning sensation; sensitivity to spicy and acidic foods and beverages; increased risk for oral candidiasis; hoarseness of voice

Sicca syndrome is a prominent component of Sjogren's disease. In other words, it is unusual to see a person with bona fide Sjogren's disease who does not have sicca syndrome.

The terms Sjogren's syndrome and sicca syndrome are sometimes used interchangeably.

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