Methylprednisolone vs prednisone

by Nathan Wei, MD, FACP, FACR

Nathan Wei is a nationally known board-certified rheumatologist and author of the Second Opinion Arthritis Treatment Kit. It's available exclusively at this website... not available in stores.

Click here: Second Opinion Arthritis Treatment Kit

Both drugs are corticosteroids with essentially the same effects and side effects.

Methylprednisolone is Medrol. It is available as an oral tablet. Methylprednisolone is also available as a parenteral preparation meaning it can be used intramuscularly or, more commonly intravenously. Prednisone is given orally.

In terms of equivalence, prednisolone 4 mgs= prednisone 5 mgs.

Basically, there are no significant differences in effects and side-effects.

In a paper published in the Cleveland Clinic Quarterly May 2002, Dr. Charles Emerman outlined the evidence and found there was no true benefit of intravenous methylprednisolone over oral prednisone in the treatment of patients with chronic obstructive pulmonary disease.

In another paper, evaluating the differences between the two drugs in the treatment of multiple sclerosis, there were no significant differences

[Effects Of Oral And IntraVenous MethylPrednisolone Treatment On Subsequent Multiple Sclerosis Relapse Rate

Sharrack B, Hughes RA, Morris RW, Soudain S, Wade-Jones O, Barnes D, Brown P, Britton T, Francis DA, Perkin GD, Rudge P, Swash M, Katifi HA, Farmer S, Frankel JP.J Neurol Sci 2000 Feb 1;173(1):73-7]

Nonetheless, in the treatment of rheumatoid arthritis flare, an intravenous pulse of methylprednisolone (1,000 mgs) can provide significant relief and buy time until disease-modifying drugs can kick in.

Get more information about methylprednisolone vs prednisone and related issues as well as...

• Insider arthritis tips that help you erase the pain and fatigue of rheumatoid arthritis almost overnight!

• Devastating ammunition against low back pain... discover 9 secrets!

• Ignored remedies that eliminate fibromyalgia symptoms quickly!

• Obsolete treatments for knee osteoarthritis that still are used... and may still work for you!

• The stiff penalties you face if you ignore this type of hip pain...

• 7 easy-to-implement neck pain remedies that work like a charm!

• And much more...

Click here Second Opinion Arthritis Treatment Kit

Return to arthritis home page.

Copyright (c) 2004 - All Rights Reserved

How to Beat Arthritis! Get our FREE monthly Ezine and get your life back!

Enter your E-mail Address
Enter your First Name (optional)

Don't worry — your e-mail address is totally secure.
I promise to use it only to send you Insider Arthritis Tips.