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Insider Arthritis Tips July and August 2015
July 15, 2015
“Logic will get you from A to B. Imagination will take you everywhere.” - Albert Einstein
Does running increase the risk of knee osteoarthritis… next
Running history doesn’t contribute to knee OA
Jeff Evans writing in Rheumatology News reported on a study presented at the American College of Rheumatology national meeting. A history of running doesn’t contribute to increased risk for knee OA and may even be protective. They study drew from data in the Osteoarthritis Initiative. Both knee pain and x-ray changes were less frequent in runners than in non-runners.
Comment: Finally… some good news if you’re a runner.
So… when is the time right for a knee replacement…
Study: 30% Of TKA Patients Experience Rapid Disease Progression, Worsening Of OA Symptoms In Two Years Prior To Procedure.
Pam Harrison writing in MedPage Today reported that research published in Osteoarthritis and Cartilage suggests that nearly “30% of patients who undergo total knee arthroplasty (TKA) experienced rapid disease progression and worsening of osteoarthritis (OA) symptoms during the 2 years leading up to the procedure itself.” Researchers found that “during the 2 years prior to TKA, worsening by at least one Kellgren and Lawrence (KL) grade occurred in 27.4% of surgical knees from the Osteoarthritis Initiatives dataset compared with 6.6% of matched nonsurgical knees.”
Comment: Basically, if you need a knee replacement, you’ll know.
A side effect of a popular pain killer…
Opioid Linked to Low Blood Sugar
Kristina Fiore writing in MedPage Today reported the mild opioid tramadol was
associated with an increased risk of hospitalization for hypoglycemia,
Comment: Interesting fact that I wasn’t aware of…
Organs on a chip…
Researchers Developing “Organs-On-A-Chip.”
Richard Harris reporting in NPR commented that researchers are developing “organs-on-a-chip” that “are designed to test drugs and help understand the basics of how organs function when they are healthy and when they are diseased.” The blog added, “‘There’s going to be a brain-on-a-chip, liver, heart and so on,’ says Danilo Tagle, who coordinates this overall effort at the National Center for Advancing Translational Sciences,” part of the NIH. Altogether, “it is funding development of 10 organ systems.”
Comment: This will help speed up drug development I hope
An epidemic that will break the bank…
$87 Billion Dollars For Total Knee Replacements by 2030?
Reported in Blood Cure… We have an epidemic of knee arthritis in the United States with over 10 million affected Americans. Many treatments are prescribed with variable efficacy for this common problem. When all else fails, knee replacement is often recommended. This procedure is overall highly successful but also expensive.
In 2009, the CDC reported the estimated costs of knee replacement in the US
to be $28.5 billion dollars. Published reports suggest there will be a need for
almost 3.5 million knee replacements in the United States by 2030. At a
conservative total cost of $25,000 per surgery, that translates into $87 billion
dollars. So, the projections suggest the costs will triple over the next 15
Comment: Obviously there is the need to find a better solution. Biotherapies such as stem cells are the areas where we need more progress.
What can the mind do for muscles?
The power of mental visualization in maintaining real-life muscle
by Stacy Brooks
Stacy Brooks writing in Medical Xpress reported researchers at the Ohio Musculoskeletal and Neurological Institute (OMNI) at Ohio University have found that the mind is critical in maintaining muscle strength following a prolonged period of immobilization and that mental imagery may be key in reducing the associated muscle loss.
Brian C. Clark and colleagues set out to test how the brain's cortex plays
into strength development.
Comment: The most powerful organ in the body is the brain.
Fat… how does that help your knees?
Fat-derived stem cells effective for osteoarthritis
Recent advances in tissue engineering have pointed towards the fact that adipose tissue may be a richer source of adult stem cells than other sources. In addition, they have a mixed population of multipotent and regenerative cells that may be more effective from a tissue repair point of view. These cells have been shown to modulate inflammation, increase the formation of blood vessels, and repair connective tissue. A recent Korean study demonstrated cartilage repair using second look arthroscopy at two years following adipose stem cell treatment.
Comment: Adipose derived stem cells are intriguing. I know my female patients are interested since a liposuction is required to harvest enough fat for stem cell procedures.
This next piece is highly unusual…
Cannabinoid Receptor Agonist May be Beneficial for Rheumatoid Arthritis
Rachel Lutz writing for HCP live reported a treatment that targets the CB2
cannabinoid receptor may be an effective treatment for rheumatoid arthritis and
synovitis, according to research published in BMC Musculoskeletal Disorders.
Comment: Far out!
Sugar water injections. Hope or hype… next
Evidence Supporting Efficacy Of Prolotherapy To Treat Chronic Joint, Muscle Pain Is Limited.
Corey Carson writing in the Washington Post reported that “prolotherapy, a treatment for chronic joint and muscle pain that involves injecting patients with dextrose...is becoming increasingly popular, even though evidence supporting its efficacy is limited.” The treatment involves “the injection of a non-active substance, most often dextrose, into an injured tissue to stimulate inflammation and trigger the body’s natural healing response.” Studies suggest that the treatment “may be effective for some parts of the body and not effective for others.” There is limited support for use of prolotherapy for ligament and tendon overuse injuries of a chronic nature.
Comment: Not sure what to say. I know two physicians who are experts in this method and according to them it works well. Using platelet rich plasma – PRP- might be a better- albeit more costly- method of treating tendon and ligament issues.
Sea Gold… It’s the purest form of Omega-3 fish oil available.
Research studies show that Omega 3 fish oil health benefits are downright amazing. Getting more Omega 3 fish oil is one the best things you can do for your health. And Sea Gold is the purest, most effective dietary fish oil manufactured. Omega-3 fish oils have been shown to be a remarkably effective and safe treatment for the inflammation of arthritis.
Omega-3 fish oils have been recommended by more rheumatologists than any other dietary supplement for the control of the inflammation that accompanies rheumatoid arthritis, psoriatic arthritis, and other forms of inflammatory arthritis. Studies show that supplementation with fish oils can markedly reduce morning stiffness and the number of painful joints for people who have rheumatoid arthritis.
You'll feel happier and be so much healthier through the benefits of Omega 3 supplements, such as Sea Gold.
· Lower blood pressure.
· Reduce triglycerides.
· Improve your memory and energy levels.
· Reduce your stress and fatigue.
· Reduces breast, colon and prostate cancer.
· Live a strong healthier life!
· Reduce your risk of arthritis, heart attack, stroke, and sudden death.
This offer is available only thru August 2015. Call our office at 301-694-5800 to speak with our product specialist.
Raspberry-Cream Cheese Muffins
Preheat oven to 350°. Combine cream cheese and butter in a large bowl. Beat with a mixer at high speed until well blended. Add sugar; beat until fluffy. Add vanilla, egg whites, and egg; beat well. Lightly spoon flour into dry measuring cups; level with a knife. Combine flour, baking powder, baking soda, and salt. With mixer on low speed, add the flour mixture and buttermilk to cream cheese mixture, beginning and ending with flour mixture. Gently fold in raspberries and walnuts. Place 24 foil cup liners in muffin cups. Spoon batter evenly into liners. Bake at 350° 25 minutes or until a wooden pick inserted in center comes out clean. Remove from pans; cool on a wire rack.
6 Unusual Signs of Dehydration
Healing Essential Oils
Your Role as a Patient: What You Can Do
Nathan Wei, MD, Rheumatology, 12:51PM Jun 3, 2015
On May 28th, I had the pleasure of attending graduation exercises for the Class of 2015 at the Sidney Kimmel Medical College of Thomas Jefferson University. Four years ago my wife and I set up a scholarship fund in my mother's memory and the first recipient of that scholarship, Christine Chang, MD, was one of the graduates. It was a memorable occasion. And it was particularly special for me because it was the 40th anniversary of my graduation from Jefferson. One touching moment occurred when the Hippocratic Oath was administered and all of the physicians in the audience were asked to join in.
When Judy and I made the decision to create the scholarship, it was done because my mother was a driving force in my becoming a doctor and also attending Jefferson. When we established the scholarship, however, we had no idea we would receive far more than we had given. Christine has become a "daughter" to us and we have been so proud of her accomplishments. In addition, we've become acquainted with her family. Her Mom and Dad are hard-working immigrants much like my parents were.
So... back to the graduation. Mr. and Mrs. Kimmel were in attendance. When the renaming of Jefferson to the Sidney Kimmel Medical College took place, there was grumbling and controversy among some graduates as to whether this was appropriate. The naming of medical institutions, however, is not new, and I personally could not see a downside. In fact, Sidney Kimmel, who grew up relatively poor in Philadelphia, rose through the ranks to become CEO of the apparel company, Jones New York, and is a real life Horatio Alger. He has been generous in providing funds for cancer research at many institutions including Sloan Kettering and Johns Hopkins.
Viktor Frankl, an eminent Viennese psychiatrist, was a Nazi concentration camp survivor. In his famous book, Man's Search For Meaning, describing his experience, he wrote "Everything can be taken from a man but one thing: the last of human freedoms- to choose one's attitude in any given set of circumstances, to choose one's own way..."
Medicine, the proudest profession, has been crushed by onerous governmental regulations, emasculated by insurance companies, and pillaged by lawyers. As physicians, we still have the ability to choose our attitude. I am determined to survive and thrive. My experience with philanthropy has given me a new understanding of what is really meaningful. I "get" why people like Sidney Kimmel do what they do. It is a privilege and honor to give.
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